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Caltech CNS Journal Club

Computation and Neural Systems at Caltech

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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Tuesday, April 17, 2012 - 12:00pm at Athenaeum

    Shuo Wang will be presenting a paper that provides further evidence for the special role of the amygdala in processing facial signals conveyed by eyes. Please RSVP by Monday, April 16th if you would like to attend.

    Fear and happiness in the eyes: An intra-cerebral event-related potential study from the human amygdala. Meletti Stefano (2012) Neuropsychologia.
    April 13, 2012
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, April 11, 2012 - 12:00pm at Athenaeum

    Alice will be presenting a paper that looks at how motivation can penetrate and guide early visual processing. Please RSVP by next next Monday evening if you are interested in joining.

    Evidence of Motivational Influences in Early Visual Perception: Hunger Modulates Conscious Access. Radel R. (2012) Psychological Science.
    March 29, 2012
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, July 13, 2011 - 12:00am at Athenaeum

    Leila will be presenting a paper that looks at how we integrate value in our everyday choices. Please RSVP by Monday evening if you are interested in joining.

    Neurobiology of value integration: when value impact valuation
    Park et al. J Neuroscience (2011), vol 31, pp. 9307-9314
    http://www.jneurosci.org/content/31/25/9307.full

    July 5, 2011
    I'd like to attend - thanks, Igor - Igor Kagan (Caltech) July 5, 2011 Comment deleted
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, May 25, 2011 - 12:00pm at Athenaeum

    Dirk will be presenting a paper that singles out frontal feedback as a signature of consciousness. Please RSVP by Monday evening if you are interested in joining.

    Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State. Boly M. (2011) Science.
    May 21, 2011
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, May 11, 2011 - 12:00pm at Atheneaum

    Mathieu will be presenting on "Circular analysis in systems neuroscience: the dangers of double dipping." Please RSVP by Monday evening if you would like to attend.

    Circular analysis in systems neuroscience: the dangers of double dipping. Kriegeskorte Nikolaus (2009) Nat Neurosci.
    May 4, 2011
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, April 27, 2011 - 12:00pm at Athenaeum

    Erik will be presenting on "ectrical synapses control hippocampal contributions to fear learning and memory." Please RSVP by Monday evening if you would like to attend.

    Electrical Synapses Control Hippocampal Contributions to Fear Learning and Memory. Bissiere S. (2011) Science.
    April 25, 2011
    Lindsay mentioned a J Neurosci article that came out yesterday (Allen et al.; http://www.jneurosci.org/content/31/17/6542.full). It has a lot more electrophysiology results, which is cool, but interestingly, the LFP behaves differently in their study. In the knockout mice the peak theta frequency is lower than controls, whereas in the blocker injection mice of the Bissiere et al. study the injected mice have higher peak theta frequency than controls. One reason the Cx36-knockout experiments aren't seen as definitive, besides there possibly being other electrotonic channels, is that the mice develop with it and may have adaptive mechanisms to compensate. So it's ... more - Erik Schomburg (Caltech) April 28, 2011 Comment deleted
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, March 9, 2011 - 12:00pm at Athenaeum

    Tamara will be presenting on "Neuronal Dynamics Underlying High- and Low-Frequency EEG Oscillations Contribute Independently to the Human BOLD Signal." Please RSVP by Monday evening if you would like to attend.

    Neuronal Dynamics Underlying High- and Low-Frequency EEG Oscillations Contribute Independently to the Human BOLD Signal. Scheeringa René (2011) Neuron.
    March 1, 2011
    I'll come. - Erik Schomburg (Caltech) March 1, 2011 Comment deleted
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, February 23, 2011 - 12:00pm at Athenaeum

    Cendri will be presenting "Theta-Burst Transcranial Magnetic Stimulation Alters Cortical Inhibition."
    Please RSVP by Tuesday evening if you would like to attend.

    Theta-Burst Transcranial Magnetic Stimulation Alters Cortical Inhibition. Benali A. (2011) Journal of Neuroscience.
    February 21, 2011
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  • Alice Lin (Caltech) created an event
    CNS Journal Club
    Wednesday, January 26, 2011 - 12:00pm at Athenaeum

    Shabnam Hakimi will be presenting "A selective role for dopamine in stimulus–reward learning." Please RSVP by Monday evening if you'd like to attend.

    A selective role for dopamine in stimulus–reward learning. Flagel Shelly B. (2011) Nature.
    January 21, 2011
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, June 2, 2010 - 12:00pm at Athenaeum

    Alice Lin will be presenting "Detecting individual memories through the neural decoding of memory states and past experience". Please RSVP by Tuesday evening if you'd like to attend.

    Detecting individual memories through the neural decoding of memory states and past experience. Rissman J (2010) Proc Natl Acad Sci U S A.
    May 31, 2010
    I'll come, thanks, Igor - Igor Kagan (Caltech) May 31, 2010 Comment deleted
    I can't make it, but I'm pretty interested in the discussion on this article. It seems a bit too good to be true, I haven't scrutinized the methods yet but we're talking about classifying data from an event-related paradigm here... and to be able to do 75% correct on a subjective memory task leaves me dubious. Please post a summary of the discussion, if possible. - Julien Dubois (Caltech) June 1, 2010 Comment deleted
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, May 19, 2010 - 12:00pm at Athenaeum

    EunJung Hwang will be presenting "Dendritic organization of sensory input to cortical neurons in vivo". Please RSVP by Tuesday 5/18 if you'd like to attend.

    Dendritic organization of sensory input to cortical neurons in vivo. Jia Hongbo (2010) Nature.
    May 10, 2010
    I'll be out of town, but wish I could attend. I saw this paper last week; it looks very interesting! - Erik Schomburg (Caltech) May 10, 2010 Comment deleted
    Too bad. Maybe we can get EunJung to post a summary after the meeting :) - John M. Delacruz (Caltech) May 10, 2010 Comment deleted
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, May 5, 2010 - 12:00pm at Athenaeum

    Sweta Agrawal will be presenting two papers. Please RSVP by Tuesday evening if you'd like to attend.

    We have all heard at one time or other about place/spatial memory work done in mice, and the role of the hippocampus in this type of memory. However, relatively recently, many scientists have begun looking at the same question in Drosophila. I thought looking over these articles might bring up some interesting questions like what exactly is place memory, how valid is the paradigm being used with Drosophila, and do insects process spatial information in any way that is similar to vertebrates?

    Spatial orientation in Drosophila. Zars T (2009) J Neurogenet.
    Place memory formation in Drosophila is independent of proper octopamine signaling. Sitaraman D (2010) J Comp Physiol A Neuroethol Sens Neural Behav Physiol.
    May 10, 2010
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, April 21, 2010 - 12:00pm at Athenaeum

    Erik Schomburg will be presenting "Impact of spikelets on hippocampal CA1 pyramidal cell activity during spatial exploration". Please RSVP by Tuesday evening if you'd like to attend.

    Note from Erik: "This study looks interesting to me because it looks at how subthreshold membrane activity, which has been difficult to observe experimentally, correlates with behavior and the spatial map, and how this drives the spiking activity."

    Impact of spikelets on hippocampal CA1 pyramidal cell activity during spatial exploration. Epsztein J (2010) Science.
    April 19, 2010
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, March 10, 2010 - 12:00pm at Athenaeum

    This week Peter Weir will be presenting two papers. Please RSVP by Tuesday evening if you'd like to attend.

    Teaser: These two papers explore hearing in insects. This little-discussed modality provides an interesting case study of sensory transduction and its behavioral consequences.

    The neural basis of Drosophila gravity-sensing and hearing. Kamikouchi Azusa (2009) Nature.
    “Singing on the Wing” as a Mechanism for Species Recognition in the Malarial Mosquito Anopheles gambiae. Pennetier Cédric (2010) Current Biology.
    April 19, 2010
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  • John M. Delacruz (Caltech) is following 3 new articles in Discussed
    Moving Through Time. Miles L. K. (2010) Psychological Science.
    Weight as an Embodiment of Importance. Jostmann Nils B. (2009) Psychological Science.
    Children learn when their teacher's gestures and speech differ. Singer MA (2005) Psychol Sci.
    March 4, 2010
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, February 24, 2010 - 12:00pm at Athenaeum

    Dominic Rizzo will be presenting three short papers. Please RSVP by Tuesday evening if you'd like to attend.

    Teaser:
    I'm going to cover a set of three papers with the common theme of embedded intelligence. They're each pretty short, but taken cumulatively point at some interesting correlations between concrete experiences and how they impact our perception of abstract ideas like value.

    Moving Through Time. Miles L. K. (2010) Psychological Science.
    Weight as an Embodiment of Importance. Jostmann Nils B. (2009) Psychological Science.
    Children learn when their teacher's gestures and speech differ. Singer MA (2005) Psychol Sci.
    February 19, 2010
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  • John M. Delacruz (Caltech) is following 5 new articles in Discussed
    Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Cardin JA (2009) Nature.
    Evaluating self-generated decisions in frontal pole cortex of monkeys. Tsujimoto Satoshi (2010) Nat Neurosci.
    Grueneberg ganglion cells mediate alarm pheromone detection in mice. Brechbühl J (2008) Science.
    Gene therapy for red-green colour blindness in adult primates. Mancuso K (2009) Nature.
    Response properties of motion-sensitive visual interneurons in the lobula plate of Drosophila melanogaster. Joesch M (2008) Curr Biol.
    February 8, 2010
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, February 3, 2010 - 12:00pm at Athenaeum

    Xoana Troncoso will be presenting "Changes of mind in decision-making". Please RSVP by Tuesday evening if you'd like to attend.

    From "Faculty of a 1000":
    "This study presents interesting findings suggesting that human subjects can change their minds after making an initial decision about which arm movement to perform by continuing to process previously acquired sensory evidence about action choices that is still in the central processing "pipeline", even if no new sensory evidence is available from the environment after the initiation of the movement."
    http://f1000biology.com/article/id/1448979

    Changes of mind in decision-making. Resulaj Arbora (2009) Nature.
    January 22, 2010
    This meeting was originally scheduled for January 27, but is being rescheduled for February 3rd. Sorry for the inconvenience! - John M. Delacruz (Caltech) January 22, 2010 Comment deleted
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, January 13, 2010 - 12:00pm at Athenaeum

    Tamara Knutsen will be presenting. Please RSVP by Tuesday evening if you'd like to attend.

    Evaluating self-generated decisions in frontal pole cortex of monkeys. Tsujimoto Satoshi (2010) Nat Neurosci.
    January 10, 2010
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, December 16, 2009 - 12:00pm at Athenaeum

    Lindsay Bremner will be presenting "Driving fast-spiking cells induces gamma rhythm and controls sensory responses". Please RSVP by Tuesday evening if you'd like to attend.

    From Lindsay:
    "This recent article was one of a pair that used the new technique of optogenetic manipulation to investigate the basis and function of cortical gamma oscillations, which are believed to be crucial for information processing in the brain. The authors test the hypothesis that gamma oscillations are induced by a specific subset of interneurons, and go on to look at the effect of oscillatory phase on the processing of a single sensory input (whisker deflection). I picked the paper because it demonstrates the powerful nature of this new technique for addressing important in vivo network questions, and also because the authors attempt to look at what the oscillations might mean for the processing of real sensory stimuli. "

    Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Cardin JA (2009) Nature.
    December 10, 2009
    How do I RSVP? - John Schulman (Caltech) December 14, 2009 Comment deleted
    Consider yourself RSVPed :) You can also email me directly. - John M. Delacruz (Caltech) December 14, 2009 Comment deleted
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, December 2, 2009 - 12:00pm at Athenaeum

    This week David Koos will be presenting "Grueneberg Ganglion Cells Mediate Alarm Pheromone Detection in Mice". Please RSVP by Tuesday evening if you'd like to attend.

    Grueneberg ganglion cells mediate alarm pheromone detection in mice. Brechbühl J (2008) Science.
    November 30, 2009
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, November 18, 2009 - 12:00pm at Athenaeum

    Marie Suver will be presenting a paper describing the response properties of motion-sensitive interneurons in Drosophila using whole-cell patch-clamp recordings. Please RSVP by Tuesday evening if you'd like to attend.

    Response properties of motion-sensitive visual interneurons in the lobula plate of Drosophila melanogaster. Joesch M (2008) Curr Biol.
    November 17, 2009
    We began with a brief overview of the fly visual system and the Reichardt correlation model. Figure-by-figure, we discussed the author's findings. In general, the group was interested in the technique and how it can help us understand the fly visual system and other computations in the brain. We also discussed what the whole-cell patch prep gains with the addition of behavior. - Marie P. Suver (Caltech) November 20, 2009 Comment deleted
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  • John M. Delacruz (Caltech) is following 1 new article in Suggested for Future
    Response properties of motion-sensitive visual interneurons in the lobula plate of Drosophila melanogaster. Joesch M (2008) Curr Biol.
    November 13, 2009
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  • John M. Delacruz (Caltech) created an event
    CNS Journal Club
    Wednesday, November 4, 2009 - 12:00pm at Athenaeum

    I will be presenting "Gene therapy for red-green colour blindness in adult primates". Please leave a comment or email me by Tuesday evening if you would like to attend.

    If you are new, the CNS Journal Club meets to discuss journal articles that are of interest to the CNS community. We typically meet twice a month on Wednesdays at Noon for lunch and discussion. To be added to the mailing list, please sign up at http://www.klab.caltech.edu/mailman/listinfo/cns-jclub

    Gene therapy for red-green colour blindness in adult primates. Mancuso K (2009) Nature.
    November 5, 2009
    In this impressive study, Mancuso et al. show they are able to give trichromatic color vision to previously color blind primates using gene therapy. In the species of monkey used in the study, males are red-green color blind while some females have normal trichromatic vision. A virus was used to insert a human L-opsin gene in adult male monkeys missing the L-opsin gene. The inserted L-opsin gene was preferentially expressed in M/L cones. After 20 weeks, the monkey's new color vision was confirmed by both retina recordings and a behavioral test. Interestingly, there was little to no time delay between when expression of the L-opsin was detectable using the retina recordings and when the monkey exhibited behavior indicative of trichromatic color vision. Given this, the authors ... more - John M. Delacruz (Caltech) November 5, 2009 Comment deleted
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  • John M. Delacruz (Caltech) is following 4 new articles in Suggested for Future
    Burst spiking of a single cortical neuron modifies global brain state. Li CY (2009) Science.
    Hippocampal replay of extended experience. Davidson TJ (2009) Neuron.
    Gene therapy for red-green colour blindness in adult primates. Mancuso K (2009) Nature.
    Energy-efficient action potentials in hippocampal mossy fibers. Alle H (2009) Science.
    October 20, 2009
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  • John M. Delacruz (Caltech) is following 10 new articles in Discussed
    The Normalization Model of Attention. Reynolds John H. (2009) Neuron.
    Abnormal Attentional Modulation of Retinotopic Cortex in Parietal Patients with Spatial Neglect. VUILLEUMIER P (2008) Current Biology.
    Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter. Káradóttir Ragnhildur (2008) Nat Neurosci.
    Control over Conflict during Movement Preparation: Role of Posterior Parietal Cortex. Coulthard Elizabeth J. (2008) Neuron.
    Spatio-temporal electrical stimuli shape behavior of an embodied cortical network in a goal-directed learning task. Bakkum Douglas J (2008) J. Neural Eng..
    What we can do and what we cannot do with fMRI. Logothetis NK (2008) Nature.
    Individual Attachment Style Modulates Human Amygdala and Striatum Activation during Social Appraisal. Vrtička Pascal (2008) PLoS ONE.
    Integrated Information in Discrete Dynamical Systems: Motivation and Theoretical Framework. Balduzzi David (2008) PLoS Computational Biology.
    A Neural Mechanism for Microsaccade Generation in the Primate Superior Colliculus. Hafed Z. M. (2009) Science.
    Anticipatory haemodynamic signals in sensory cortex not predicted by local neuronal activity. Sirotin Yevgeniy B. (2009) Nature.
    September 1, 2009
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  • John M. Delacruz (Caltech)

    Journal Club is on break for the summer and will be resuming in the Fall. Start thinking of papers you'd like to discuss!

    September 1, 2009
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  • John M. Delacruz (Caltech) created an event
    Journal Club
    Wednesday, May 27, 2009 - 12:00pm at Athenaeum

    After a few weeks hiatus, this week Jeroen Van Boxtel will be presenting Reynolds & Heeger's normalization model of attention.

    Please let me know by Tuesday evening if you would like to attend. Lunch will be served.

    The Normalization Model of Attention. Reynolds John H. (2009) Neuron.
    September 1, 2009
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  • John M. Delacruz (Caltech) created an event
    Journal Club
    Wednesday, April 22, 2009 - 12:00pm at Athenaeum

    This week Dominic Rizzo will be presenting.

    From the author's summary: "We introduce a measure that quantifies how much integrated information is generated by a discrete dynamical system in the process of transitioning from one state to the next [... and ...] present numerical analyses of basic examples, which match well against neurobiological evidence concerning the neural substrates of consciousness."

    Please email me by Tuesday evening if you would like to attend. Lunch will be served.

    Integrated Information in Discrete Dynamical Systems: Motivation and Theoretical Framework. Balduzzi David (2008) PLoS Computational Biology.
    September 1, 2009
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  • John M. Delacruz (Caltech) created an event
    Journal Club
    Wednesday, April 8, 2009 - 12:00pm at Athenaeun

    This week David Koos will be presenting.

    Please email me by Tuesday evening if you would like to attend. Lunch will be served.

    Temporally precise in vivo control of intracellular signalling. Airan RD (2009) Nature.
    April 6, 2009
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