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Elisa Franco

California Institute of Technology
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  • BioControl (1)
  • My Publications (6)

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  • Caltech BioControl

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  • is following 5 new articles in My Publications
    Geometry of unsteady fluid transport during fluid–structure interactions. FRANCO ELISA (2007) J. Fluid Mech..
    Distributed Fault Diagnosis using Sensor Networks and Consensus-based Filters. Franco Elisa (2006) Proceedings of the 45th IEEE Conference on Decision and Control.
    Design and stability analysis of cooperative receding-horizon control of linear discrete-time agents. Franco Elisa (2007) Int. J. Robust Nonlinear Control.
    Cooperative Constrained Control of Distributed Agents With Nonlinear Dynamics and Delayed Information Exchange: A Stabilizing Receding-Horizon Approach. Franco Elisa (2008) IEEE Trans. Automat. Contr..
    Stable receding-horizon cooperative control of a class of distributed agents. Franco E. () Proceedings of the 2005, American Control Conference, 2005..
    March 4, 2010
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  • created an event in Caltech BioControl
    Meeting
    Friday, February 12, 2010 - 9:00am at Steele library
    Is genetic evolution predictable?. Stern DL (2009) Science.
    February 5, 2010
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  • created an event in Caltech BioControl
    next meeting?
    Friday, November 27, 2009 - 10:00am at Steele Library

    What about this paper? If you have better ideas, let me know.

    Evolvability and hierarchy in rewired bacterial gene networks. Isalan M (2008) Nature.
    November 20, 2009
    We did that one last year - it made it into the top of '07-'08. I'd suggest the new paper from Wingreen and Bassler (et al.). - Joshua K. Michener (Caltech) November 20, 2009 Comment deleted
    Oh I must have missed that meeting! Thanks for pointing that out... - Elisa Franco (Caltech) November 28, 2009 Comment deleted
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  • created an event in Caltech BioControl
    Next meeting
    Friday, October 30, 2009 - 10:00am at Steele Library

    Paper about noise...

    Molecular Systems Biology 5 Article number: 318 doi:10.1038/msb.2009.75
    Published online: 13 October 2009
    Citation: Molecular Systems Biology 5:318

    Listening to the noise: random fluctuations reveal gene network parameters

    Brian Munsky1, Brooke Trinh2 & Mustafa Khammash3

    October 26, 2009
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  • created an event in Caltech BioControl
    Next meeting
    Friday, October 16, 2009 - 10:00am at Steele library
    Kinetic Buffering of Cross Talk between Bacterial Two-Component Sensors. Groban Eli S. (2009) Journal of Molecular Biology.
    October 9, 2009
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  • created an event in Caltech BioControl
    Next meeting
    Wednesday, October 7, 2009 - 10:30am at Steele Library

    Potential date for starting our meetings again! I picked a random paper...

    Synthetic biology: The yin and yang of nature. Gore Jeff (2009) Nature.
    September 10, 2009
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  • is following 6 new articles in Caltech BioControl: Best of 07-08
    Evolvability and hierarchy in rewired bacterial gene networks. Isalan M (2008) Nature.
    Molecular computation of solutions to combinatorial problems. Adleman LM (1994) Science.
    Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Santos SD (2007) Nat Cell Biol.
    Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Bashor CJ (2008) Science.
    Real-time kinetics of gene activity in individual bacteria. Golding I (2005) Cell.
    The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae. Mettetal JT (2008) Science.
    September 10, 2009
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  • is following 10 new articles in Caltech BioControl: Best of 06-07
    Accurate prediction of gene feedback circuit behavior from component properties. Rosenfeld N (2007) Mol Syst Biol.
    Enzyme-free nucleic acid logic circuits. Seelig G (2006) Science.
    Transient dynamics of genetic regulatory networks. Bennett MR (2007) Biophys J.
    Physical limits to biochemical signaling. Bialek W (2005) Proc Natl Acad Sci U S A.
    Stochastic focusing: fluctuation-enhanced sensitivity of intracellular regulation. Paulsson J (2000) Proc Natl Acad Sci U S A.
    Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Angeli D (2004) Proc Natl Acad Sci U S A.
    Improving lycopene production in Escherichia coli by engineering metabolic control. Farmer WR (2000) Nat Biotechnol.
    RNA synthetic biology. Isaacs FJ (2006) Nat Biotechnol.
    Network motifs: simple building blocks of complex networks. Milo R (2002) Science.
    Guiding bacteria with small molecules and RNA. Topp S (2007) J Am Chem Soc.
    September 10, 2009
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  • created the Caltech BioControl journal club.
    September 10, 2009
  • is following 1 new article in BioControl
    Complexity in bacterial cell-cell communication: quorum signal integration and subpopulation signaling in the Bacillus subtilis phosphorelay. Bischofs IB (2009) Proc Natl Acad Sci U S A.
    September 10, 2009
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  • is following 1 new article in My Publications
    . Franco E. () 2004 43rd IEEE Conference on Decision and Control (CDC) (IEEE Cat. No.04CH37601).
    August 1, 2009
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  • joined JournalFire!
    August 1, 2009
  • created an event in Caltech BioControl
    Week3-27
    Wednesday, May 13, 2009 - 10:00am at Steele Library

    Phosphorelays

    Complexity in bacterial cell-cell communication: quorum signal integration and subpopulation signaling in the Bacillus subtilis phosphorelay. Bischofs IB (2009) Proc Natl Acad Sci U S A.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-26
    Wednesday, May 6, 2009 - 10:00am at Steele Library

    signaling network
    integration of multiple signals
    EGF, Insulin MAPK cascades

    Systems-level interactions between insulin-EGF networks amplify mitogenic signaling. Borisov N (2009) Mol Syst Biol.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-25
    Wednesday, April 29, 2009 - 10:00am at Steele Library

    * Leibler
    * evolution of cooperation

    Simpson's paradox in a synthetic microbial system. Chuang JS (2009) Science.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-24
    Wednesday, April 22, 2009 - 10:00am at Steele Library

    Ultrasensitivity and molecular titration

    Molecular titration and ultrasensitivity in regulatory networks. Buchler NE (2008) J Mol Biol.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-23
    Wednesday, April 15, 2009 - 10:00am at Steele Library

    Negative feedback and linearization

    Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression. Nevozhay D (2009) Proc Natl Acad Sci U S A.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-22
    Wednesday, April 8, 2009 - 10:00am at Steele Library

    Stress transient transcriptional responses

    Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. Shalem O (2008) Mol Syst Biol.
    October 8, 2009
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  • created an event in Caltech BioControl
    Week3-21
    Wednesday, April 8, 2009 - 10:00am at Steele Library

    Modeling and experiments to understand mechanisms of gene regulation by sRNA in bacteria

    Quantitative characteristics of gene regulation by small RNA. Levine E (2007) PLoS Biol.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-20
    Wednesday, March 18, 2009 - 10:00am at Steele Library

    Control of Stem Cell Proliferation and Lineages

    Cell lineages and the logic of proliferative control. Lander AD (2009) PLoS Biol.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-19
    Wednesday, February 25, 2009 - 10:00am at Steele Library

    Synthetic Controller to tune fitness tradeoffs.

    Or, following up on our "Endy" topic with "Smolke" :P -F

    Synthetic control of a fitness tradeoff in yeast nitrogen metabolism. Bayer TS (2009) J Biol Eng.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-18
    Wednesday, February 18, 2009 - 10:00am at Steele Library

    Drew Endy

    * Is Drew the author or the topic?

    Determination of cell fate selection during phage lambda infection. St-Pierre F (2008) Proc Natl Acad Sci U S A.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-17
    Wednesday, February 4, 2009 - 10:00am at Steele Library

    robust gene networks

    Survival of the sparsest: robust gene networks are parsimonious. Leclerc RD (2008) Mol Syst Biol.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-16
    Wednesday, January 28, 2009 - 10:00am at Steele Library

    complex regulation of genes in yeast due to nucleosome positioning

    Chromatin decouples promoter threshold from dynamic range. Lam FH (2008) Nature.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-15
    Wednesday, January 21, 2009 - 10:00am at Steele Library

    synthetic promoters

    Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Gertz J (2009) Nature.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-13
    Wednesday, December 3, 2008 - 10:00am at Steele Library

    Quantitative models of gene expression in Yeast

    A quantitative model of transcription factor-activated gene expression. Kim HD (2008) Nat Struct Mol Biol.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-12
    Wednesday, November 19, 2008 - 10:00am at Steele Library

    * Activity motifs
    * principles of timing
    * transcriptional control
    * yeast
    * metabolic networks

    Comments:

    Promising, but ultimately disappointing. The curve fitting to the mRNA data was not convincing (the shape of the data did not match the fit). Measurements (mRNA and ChIP-chip in particular) should probably have large error bars, bringing fine distinctions in timing or affinity into question. Time resolution was also questionable - the first measurement was taken at 15 minutes, but differences in activation time of 3 minutes vs. 4 minutes were treated as significant. No data was presented to support the claim on correlation between binding affinity motifs and transcriptional activation motifs, and the conclusions were presented in a confusing fashion (why claim that 20/48 data sets showed correlation, rather than breaking things out by individual motifs?).

    Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Chechik G (2008) Nat Biotechnol.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-11
    Wednesday, November 12, 2008 - 10:00am at Steele Library

    A better repressilator

    A fast, robust and tunable synthetic gene oscillator. Stricker J (2008) Nature.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-10
    Wednesday, November 5, 2008 - 9:00am at Steele Library

    Biophysics of gene regulation

    A stochastic single-molecule event triggers phenotype switching of a bacterial cell. Choi PJ (2008) Science.
    October 9, 2009
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  • created an event in Caltech BioControl
    Week3-9
    Wednesday, October 29, 2008 - 10:00am at Steele Library

    Cellular computing

    Higher-order cellular information processing with synthetic RNA devices. Win MN (2008) Science.
    October 9, 2009
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